ABSTRACT
Objective:To construct a medical records management system based on document database so as to promote standardization of medical records management and improve management efficiency.Methods:Microsoft.Net platform and SQL SERVER database were selected, and three-tier framework of.Net webservic was adopted to design a medical records management system which contained three modules included filing, review and system management for medical records and which based on document database.Results:The application of this system significantly reduced the operational process of manual business of the staffs, and optimized the workflow, and extremely improved the work efficiency and significantly increased the utilization rate of medical records.Conclusion:The application of medical records management system based on document database not only can improve the work efficiency of staff but also can make better use of medical records, and better promote information construction and improvement of medical service quality of hospital.
ABSTRACT
In this study,a method using ultra performance liquid chromatography tandem quadrupole time-of-flight mass spectrometry( UPLC-Q-TOF-MS/MS) was established to identify complicated chemical constituents of Wikstroemia indica. Chromatographic separation was performed on an AcclaimTMRSLC 120-C18 column( 2. 1 mm×100 mm,2. 2 μm) using gradient elution with 0. 2% ammonium formate buffer salt solution( A)-0. 2% ammonium formate buffer salt solution methanol( B) as mobile phase. The column temperature was maintained at 30 ℃. The analytes were determined by positive and negative ion modes with electro-spray ionization source. A total of 52 compounds( including eleven coumarins,thirteen flavonoids,ten lignans,two amides,four phenolic acids,six sesquiterpenes and six other compounds) were identified or tentatively characterized from the water extract of W. indica by comparing their retention times and MS spectra with those of authentic standards or literature datas. Three compounds were found for the first time from W.indica namely isomer of indicanone,β-hydroxypropiovanillone and epiprocurcumenol. Furthermore,the fragmentation rules of some compounds were speculated and summarized. In addition,the cleavage pathways of guaiane sesquiterpenes were described for the first time,which can provide reference for studying the fragmentation pathways of similar compounds. This study provides an easy way to identify chemical constituents of traditional Chinese medicine and a basis for the further study on chemical fundamentals of W. indica.